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Unlike many comic book magicians, Constantine is rarely seen using magical spells, and almost never in combat. Constantine faces most of his challenges relying primarily on his cunning, his knowledge of the occult, manipulation and an extensive list of contacts.
Constantine's blood is demonically tainted, first by a blood transfusion from the demon Nergal and later from sex with a succubus. Should his blood be injected into another person, it will instantaneously heal them, although they will then suffer the same taint.
John has generally been shown to be a poor fighter and generally avoids physical battles. However, he has on occasion managed to win a fight, either by using a magical weapon (Hellblazer #217) or by fighting dirty (Hellblazer #57 and the graphic novel All His Engines).
Some examples of Constantine's magic:
Used a pendulum and map to divine the location of a magical disturbance. (Hellblazer #4 and #182)
Summoned the demon Nergal to destroy a monster for him, but lost control. (Hellblazer #11)
Placed a curse on his father that caused him to waste away. (Hellblazer #31)
Placed a magical sigil on a succubus that prevented the forces of Heaven and Hell from tracking her. (Hellblazer #60)
Raised a golem. (Hellblazer #167)
Erased a man's traumatic memories. (Hellblazer #217)
Ironically, for all of his abilities, Constantine never learned to drive and in the past has often relied on his old friend Chas for transport.